About

About

The Lifespan Brain Institute (LiBI) is dedicated to studying how the brain and behavior develop and change over time and in response to different illnesses. This collaboration between the Children’s Hospital of Philadelphia and the University of Pennsylvania bridges the gap between pediatric and adult research, making it possible for researchers to begin studying participants at a young age and to continue to follow them into adulthood. With this lifespan approach, researchers are able to study what early risk factors might contribute to the development of mental disorders, what factors might protect children from developing mental disorders or help them cope more effectively, and how illnessess might affect brain and behavior.

Current Studies / Online Screener

Current Studies / Online Screener

All of the research we conduct at the Lifespan Brain Institute aims to better understand:

  • How the brain functions and develops, in both healthy people and people with brain disorders
  • How different illnesses affect the brain
  • Early identification and treatment of mental illnesses
  • Risk and protective factors for developing mental illnesses
  • How to improve treatment options and outcomes

Recent Publications

Recent Publications

  • Contributions of PTSD polygenic risk and environmental stress to suicidality in preadolescents

  • Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3-90 years

  • Dopamine D1R Receptor Stimulation as a Mechanistic Pro-cognitive Target for Schizophrenia

  • Commentary: Schizophrenia prevention and prodromal psychosis in children and adolescents