Barbara H Chaiyachati, M.D., Ph.D. Post-Doctoral Fellow

Barbara is joining the LiBI Team for a postdoctoral fellowship. She completed her M.D. and Ph.D. at Yale as well as a Doris Duke Fellowship for the Promotion of Child Wellbeing. She completed her pediatrics residency at CHOP prior to her current position as a Fellow in Child Abuse Pediatrics.

Barbara's research seeks to identify actionable biologic targets for intervention to improve child well-being and abrogate or even prevent negative health consequences of adverse childhood experiences.




M.D. - Yale School of Medicine - 2015
Ph.D. - Yale University - 2013 - Cell Biology
B.A. - Macalester College - 2006 - Biology

Selected Publications



1. Hirschman, B.A.; Pollock, B.H.; Tomlinson, G.E.: The spectrum of APC mutations in children with hepatoblastoma from familial adenomatous polyposis kindreds. The Journal of Pediatrics 147(2): 263-6, Aug 2005.


2. Swinney, R.M.; Hsu S.C.; Hirschman B.A.; Chen T.T-C.; Tomlinson G.E.: MDM2 promoter variation and age of diagnosis of acute lymphoblastic leukemia. Leukemia 19(11): 1996-8, Nov 2005.


3. Chaiyachati, B.H., Kaundal, R.K.; Zhao, J.; Wu, J.; Flavell, R.; Chi, T.: LoxP-FRT Trap (LOFT): a simple and flexible system for conventional and reversible gene targeting. BMC Biology 10: 96, Nov 2012. PMCID: PMC3529186


4. Wan, M.; Kaundal, R.; Huang, H.; Zhao, J.; Yang, X.; Chaiyachati, B.H.; Li, S.; Chi, T.: A general approach for controlling transcription and probing epigenetic mechanisms: application to the CD4 locus. Journal of immunology (Baltimore, Md.: 1950) 190(2): 737-47, Jan 2013. PMCID: PMC3744393


5. Chaiyachati, B.H.; Jani, A.; Wan, Y.; Huang, H.; Flavell, R.; Chi, T.: BRG1-mediated immune tolerance: facilitation of Treg activation and partial independence of chromatin remodelling. The EMBO journal 32(3): 395-408, Feb 2013. PMCID: PMC3567501


6. Wan, M.; Gu, H.; Wang, J.; Huang, H.; Zhao, J.; Kaundal, R.K.; Yu, M.; Kushwaha, R.; Chaiyachati, B.H.; Deerhake, E.; Chi, T: Inducible mouse models illuminate parameters influencing epigenetic inheritance. Development (Cambridge, England) 140(4): 843-52, Feb 2013. PMCID: PMC3557779


7. Trobaugh-Lotrario, A.D.; Chaiyachati, B.H.; Meyers, R.L.; Häberle, B.; Tomlinson, G.E.; Katzenstein, H.M.; Malogolowkin, M.H.; von Schweinitz Dietrich, K.M.; Feusner, J.H.: Outcomes for patients with congenital hepatoblastoma. Pediatric blood & cancer 60(11): 1817-25, Nov 2013.


8. Chaiyachati, B.H.; Asnes, A.G.; Moles, R.L.; Schaeffer, P.; Leventhal, J.M.: Gray cases of child abuse: Investigating factors associated with uncertainty. Child abuse & neglect 51: 87-92, Jan 2016.


9. Chaiyachati, B.H.; Gaither, J.R.; Hughes, M.; Foley-Schain, K.; Leventhal J.M.: Preventing child maltreatment: Examination of an established statewide home-visiting program. Child abuse & neglect 79: 476-484, May 2018. PMCID: PMC5894115


10. Chaiyachati B.H., Wood J.N., Mitra N., Chaiyachati K.H.: All-Cause Mortality among Children in the United States Foster Care System, 2003-2016. JAMA Pediatrics April 2020.


11. Chaiyachati, B.H.; Agawu, A.; Zorc, J.; Balamuth, F.: Trends in Pediatric Emergency Department Utilization after Institution of COVID-19 Mandatory Social Distancing  The Journal of Pediatrics July 2020. PMCID: PMC7370904