Publications

Scott, J.C., Rosen, A.F.G., Moore, T.M., Roalf, D.R., Satterthwaite, T.D., Calkins, M.E., Ruparel, K., Gur, R.E., & Gur, R.C. (2019) Cannabis use in youth is associated with limited alterations in brain structure. Neuropsychopharmacology, 44(8), 1362-1369. https://doi.org/10.1038/s41386-019-0347-2

Barzilay, R., Calkins, M.E., Moore, T.M., Boyd, R.C., Jones, J.D., Benton, T.D., Oquendo, M.A., Gur, R.C., & Gur, R.E. (2019) Neurocognitive functioning in community youth with suicidal ideation: gender and pubertal effects. British Journal of Psychiatry, 215, 552-558. doi: 10.1192/bjp.2019.55

Gur, R.E., Moore, T.M., Rosen, A.F.G., Barzilay, R., Roalf, D.R., Calkins, M.E., Ruparel, K., Scott, J.C., Almasy, L., Satterthwaite, T.D., Shinohara, R.T., & Gur, R.C. (2019) Burden of environmental adversity associated with psychopathology, maturation, and brain parameters in youths. JAMA Psychiatry, 76(9), 966-975. doi: 10.1001/jamapsychiatry.2019.0943

Tooley, U.A., Mackey, A.P., Ciric, R., Ruparel, K., Moore, T.M., Gur, R.C., Gur, R.E., Satterthwaite, T.D., & Bassett, D.S. (2019) Associations between neighbornood SES and functional brain network development. Cerebral Cortex, [Epub ahead of print] doi:10.1093/cercor/bhz066

Kaczkurkin, A.N., Park, S.S., Sotiras, A., Moore, T.M., Calkins, M.E., Cieslak, M., Rosen, A.F.G., Ciric, R., Xia, C.H., Cui, Z., Sharma, A., Wolf, D.H., Ruparel, K., Pine, D.S., Shinohara, R.T., Roalf, D.R., Gur, R.C., Davatzikos, C., Gur, R.E., & Satterthwaite, T.D. (2019) Evidence for dissociable linkage of dimensions of psychopathology to brain structure in youths. American Journal of Psychiatry, 176(12), 1000-1009. doi: 10.1176/appi.ajp.2019.18070835

Villalón-Reina, J., Martínez, K., Qu, X., Ching, C., Nir, T., Kothapalli, D., … Campbell, L. (2019) Altered white matter microstructure in 22q11.2 deletion syndrome: a multisite diffusion tensor imaging study. Molecular Psychiatry. https://doi.org/10.1038/s41380-019-0450-0.

Gu, S., Xia, C.H., Moore, T.M., Gur, R.C., Gur, R.E., Satterthwaite, T.D., & Bassett, D.S. (2019) Unifying the notions of modularity and core-periphery structure in functional brain networks during youth. Cerebral Cortex, [Epub ahead of print] doi: 10.1093/cercor/bhz150

Gur, R.E. & Gur, R.C. (2019) Functional MRI Predicting Intervention Outcome in Early Psychosis. American Journal of Psychiatry, 176(10), 780-782. doi: 10.1176/appi.ajp.2019.19080807

Kaczkurkin, A.N., Sotiras, A., Baller, E.B., Barzilay, R., Calkins, M.E., Chand, G.B., Cui, Z., Erus, G., Fan, Y., Gur, R.E., Gur, R.C., Moore, T.M., Roalf, D.R., Rosen, A.F.G., Ruparel, K., Shinohara, R.T., Varol, E., Wolf, D.H., Davatzikos, C., & Satterthwaite, T.D. (2019) Neurostructural Heterogeneity in Youths With Internalizing Symptoms. Biological Psychiatry, [Epub ahead of print]. https://doi.org/10.1016/j.biopsych.2019.09.005

Pomponio, R., Erus, G., Habes, M., Doshi, J., Srinivasan, D., Mamourian, E., Bashyam, V., Nasrallah, I.M., Satterthwaite, T.D., Fan, Y., Launer, L.J., Masters, C.L., Maruff, P., Zhuo, C., Völzke, H., Johnson, S.C., Fripp, J., Koutsouleris, N., Wolf, D.H., Gur, R., Gur, R., Morris, J., Albert, M.S., Grabe, H.J., Resnick, S.M., Bryan, R.N., Wolk, D.A., Shinohara, R.T., Shou, H., & Davatzikos, C. (2019) Harmonization of large MRI datasets for the analysis of brain imaging patterns throughout the lifespan. NeuroImage, [Epub ahead of print]. https://doi.org/10.1016/j.neuroimage.2019.116450

Zhao, Y. et al. (2019) Complete sequence of the 22q11.2 allele in 1,053 subjects with 22q11.2 deletion syndrome reveals modifiers of conotruncal heart defects.  American Journal of Human Genetics, 106(1), 26-40. https://doi.org/10.1016/j.ajhg.2019.11.010

Baum, G. L., Cui, Z., Roalf, D. R., Ciric, R., Betzel, R. F., Larsen, B., . . . Satterthwaite, T. D. (2019). Development of structure-function coupling in human brain networks during youth. Proceedings of the National Academy of Sciences, 117(1), 771-778. doi: 10.1073/pnas.1912034117 

Taylor, J.H., Asabere, N., Calking, M.E., Moore, T.M., Tang, S.X., Xavier, R.M., Merikangas, A.K., Wolf, D.H., Almasy, L., Gur, R.C., & Gur, R.E. (2019) Characteristics of youth with reported family history of psychosis spectrum symptoms in the Philadelphia Neurodevelopmental Cohort. Schizophrenia Research. [Epub ahead of print]  https://doi.org/10.1016/j.schres.2019.12.021

Barzilay, R., Lawrence, G. M., Berliner, A., Gur, R. E., Leventer-Roberts, M., Weizman, A., & Feldman, B. (2019). Association between prenatal exposure to a 1-month period of repeated rocket attacks and neuropsychiatric outcomes up through age 9: A retrospective cohort study. European Child & Adolescent Psychiatry. doi: http://dx.doi.org.proxy.library.upenn.edu/10.1007/s00787-019-01426-1.

Quarmley, M., Gur, R. C., Turetsky, B. I., Watters, A. J., Bilker, W. B., Elliott, M. A., … Wolf, D. H. (2019). Reduced Safety Processing During Aversive Social Conditioning in Psychosis and Clinical Risk. Neuropsychopharmacology, 44(13), 2247–2253. doi: https://doi.org/10.1038/s41386-019-0421-9

Yudien, M.A., Moore, T.M., Port, A.M., Ruparel, K, Gur, R.E., & Gur, R.C. (2019). Development and Public Release of the Penn Reading Assessment Computerized Adaptive Test (PRA-CAT) for Premorbid IQ. Psychological Assessment, 31(9),1168-1173. http://dx.doi.org/10.10370pas0000738

Barzilay, R., Patrick, A., Calkins, M. E., Moore, T. M., Gur, R. C., & Gur, R. E. (2019). Association between early-life trauma and obsessive compulsive symptoms in community youth. Depression and Anxiety. doi: 10.1002/da.22907. [Epub ahead of print]

Siegel, S. J., Winey, K. I., Gur, R. E., Lenox, R. H., Bilker, W. B., Ikeda, D., … Zhang, W.-X. (2002). Surgically implantable long-term antipsychotic delivery systems for the treatment of schizophrenia. Neuropsychopharmacology, 26(6), 817–823.

Siegel, S. J., Connolly, P., Liang, Y., Lenox, R. H., Gur, R. E., Bilker, W. B., … Turetsky, B. I. (2003). Effects of strain, novelty, and NMDA blockade on auditory-evoked potentials in mice. Neuropsychopharmacology, 28(4), 675–682.

Connolly, P. M., Maxwell, C. R., Kanes, S. J., Abel, T., Liang, Y., Tokarczyk, J., … Siegel, S. J. (2003). Inhibition of auditory evoked potentials and prepulse inhibition of startle in DBA/2J and DBA/2Hsd inbred mouse substrains. Brain Research, 992(1), 85–95.

Maxwell, C. R., Liang, Y., Weightman, B. D., Kanes, S. J., Abel, T., Gur, R. E., … Siegel, S. J. (2004). Effects of chronic olanzapine and haloperidol differ on the mouse N1 auditory evoked potential. Neuropsychopharmacology, 29(4), 739–746.

Talbot, K., Eidem, W. L., Tinsley, C. L., Benson, M. A., Thompson, E. W., Smith, R. J., … Arnold, S. E. (2004). Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hippocampal formation in schizophrenia. The Journal Of Clinical Investigation, 113(9), 1353–1363.

Connolly, P. M., Maxwell, C., Liang, Y., Kahn, J. B., Kanes, S. J., Abel, T., . . . Siegel, S. J. (2004). The effects of ketamine vary among inbred mouse strains and mimic schizophrenia for the P80, but not P20 or N40 auditory ERP components. Neurochemical Research, 29(6), 1179-1188.

Hahn, C.-G., Wang, H.-Y., Cho, D.-S., Talbot, K., Gur, R. E., Berrettini, W. H., … Arnold, S. E. (2006). Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia. Nature Medicine, 12(7), 824–828.

Carlson, G. C., Talbot, K., Halene, T. B., Gandal, M. J., Kazi, H. A., Schlosser, L., … Siegel, S. J. (2011). Dysbindin-1 mutant mice implicate reduced fast-phasic inhibition as a final common disease mechanism in schizophrenia. PNAS Proceedings of the National Academy of Sciences of the United States of America, 108(43), E962–E970.

Liu, J., Richmond, T. S., Raine, A., Cheney, R., Brodkin, E. S., Gur, R. C., & Gur, R. E. (2013). The Healthy Brains and Behavior Study: objectives, design, recruitment, and population coverage. International Journal of Methods in Psychiatric Research, 22(3), 204–216.

Billingslea, E. N., Tatard-Leitman, V. M., Anguiano, J., Jutzeler, C. R., Suh, J., Saunders, J. A., … Siegel, S. J. (2014). Parvalbumin cell ablation of NMDA-R1 causes increased resting network excitability with associated social and self-care deficits. Neuropsychopharmacology, 39(7), 1603–1613.

Tatard-Leitman, V. M., Jutzeler, C. R., Suh, J., Saunders, J. A., Billingslea, E. N., Morita, S., … Siegel, S. J. (2015). Pyramidal cell selective ablation of N-methyl-D-aspartate receptor 1 causes increase in cellular and network excitability. Biological Psychiatry, 77(6), 556–568.

Gur, R. C., & Gur, R. E. (2016). Social cognition as an RDoC domain. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 171(1), 132–141.

Tunç, B., Solmaz, B., Parker, D., Satterthwaite, T. D., Elliott, M. A., Calkins, M. E., … Verma, R. (2016). Establishing a link between sex-related differences in the structural connectome and behaviour. Philosophical Transactions B: Biological Sciences, 371(1688).

Roalf, D. R., Quarmley, M., Calkins, M. E., Satterthwaite, T. D., Ruparel, K., Elliott, M. A., … Turetsky, B. I. (2017). Temporal lobe volume decrements in psychosis spectrum youths. Schizophrenia Bulletin, 43(3), 601–610.

Moore, T., Martin, I., Gur, O., Jackson, C., Moore, T., Martin, I., … Gur, R. (2016). Characterizing social environment's association with neurocognition using census and crime data linked to the Phildelphia Neurodevelopmental Cohort. Psychological Medicine, 46(3), 599–610.

Kaczkurkin, A. N., Moore, T. M., Ruparel, K., Ciric, R., Calkins, M. E., Shinohara, R. T., … Satterthwaite, T. D. (2016). Elevated amygdala perfusion mediates developmental sex differences in trait anxiety. Biological Psychiatry, 80(10), 775–785.

Calkins, M. E., Moore, T. M., Satterthwaite, T. D., Wolf, D. H., Turetsky, B. I., Roalf, D. R., … Gur, R. E. (2017). Persistence of psychosis spectrum symptoms in the Phildelphia Neurodevelopmental Cohort: a prospective two-year follow-up.  World Psychiatry, 16(1), 62–76.

Baum, G. L., Roalf, D. R., Cook, P. A., Ciric, R., Rosen, A. F. G., Xia, C., … Satterthwaite, T. D. (2018). The impact of in-scanner head motion on structural connectivity derived from diffusion MRI. NeuroImage, 173, 275–286.

Reardon, P. K., Seidlitz, J., Vandekar, S., Liu, S., Patel, R., Park, M. T. M., … Raznahan, A. (2018). Normative brain size variation and brain shape diversity in humans. Science, 360(6934), 122-1227.

Nassar, R., Kaczkurkin, A. N., Xia, C. H., Sotiras, A., Pehlivanova, M., Moore, T. M., … Satterthwaite, T. D. (2019). Gestational age is dimensionally associated with structural brain network abnormalities across development. Cerebral Cortex, 29(5), 2102–2114.

Bassett, D. S., Xia, C. H., & Satterthwaite, T. D. (2018). Understanding the emergence of neuropsychiatric disorders with network neuroscience. Biological Psychiatry. Cognitive Neuroscience And Neuroimaging, 3(9), 742–753.

Kaczkurkin, A. N., Raznahan, A., & Satterthwaite, T. D. (2019). Sex differences in the developing brain: insights from multimodal neuroimaging. Neuropsychopharmacology, 44(1), 71–85.

Scott, J. C., Slomiak, S. T., Jones, J. D., Rosen, A. F. G., Moore, T. M., & Gur, R. C. (2018). Association of Cannabis With Cognitive Functioning in Adolescents and Young Adults:  A Systematic Review and Meta-analysis.  JAMA Psychiatry, 75(6), 585–595.  Advance online publication.

Jones, J. D., Boyd, R. C., Calkins, M. E., Ahmed, A., Moore, T. M., Barzilay, R., . . . Gur, R. E. (2019). Parent-adolescent agreement about adolescents’ suicidal thoughts in a large community sample. Pediatrics, 143(2).

Moore, T. M., Calkins, M. E., Reise, S. P., Gur, R. C., & Gur, R. E. (2018). Development and public release of a computerized adaptive (CAT) version of the Schizotypal Personality Questionnaire. Psychiatry Research, 263, 250–256.

Moberg, P. J., Richman, M. J., Roalf, D. R., Morse, C. L., Graefe, A. C., Brennan, L., … Gur, R. E. (2018).Neurocognitive functioning in patients with 22q11.2 Deletion Syndrome: A meta-analytic review. Behavior Genetics, 48(4), 259–270. Advance online publication, doi: 10.1007/s10519-018-9903-5.

Watters, A. J., Rupert, P. E., Wolf, D. H., Calkins, M. E., Gur, R. C., Gur, R. E., & Turetsky, B. I. (2018). Social Aversive Conditioning in Youth at Clinical High Risk for Psychosis and with Psychosis: An ERP Study. Schizophrenia Research, 202, 291–296.Advanced online publication, doi: 10.1016/j.schres.2018.06.027

Pehlivanova, M., Wolf, D. H., Sotiras, A., Kaczkurkin, A. N., Moore, T. M., Ciric, R., … Satterthwaite, T. D. Diminished cortical thickness is associated with impulsive choice in adolescence. The Journal of Neuroscience, 38(10), 2471–2481.

Rosen, A. F. G., Roalf, D. R., Ruparel, K., Blake, J., Seelaus, K., Villa, L. P., … Satterthwaite, T. D. (2018). Quantitative assessment of structural image quality. NeuroImage, 169, 407–418.

Ahmed, A., Moore, T.M., Lewis, J., Butler, L., Benton, T.D., & Boyd, R.C. (2018). Psychometric properties of Bully, Fighting, and Victimization scales among clinically referred youth.  Journal of Aggression, Maltreatment and Traum, 1 - 15. Advanced online publication https://doi.org/10.1080/10926771.2017.1420718

Niarchou, M., Moore, T. M., Tang, S. X., Calkins, M. E., McDonald-McGinn, D. M., Zackai, E. H., … Gur, R. E. (2019). The dimensional structure of psychopathology in 22q11.2 Deletion Syndrome. Journal of Psychiatric Research, 118, 8. doi: 10.1016/j.jpsychires.2017.04.006. Epub 2017 Apr 15.

Niarchou, M., Calkins, M. E., Moore, T. M., Tang, S. X., McDonald-McGinn, D. M., Zackai, E. H., … Gur, R. E. (2017). Attention Deficit Hyperactivity Disorder Symptoms and Psychosis in 22q11.2 Deletion Syndrome. Schizophrenia Bulletin, 44(4), 824–833. doi: 10.1093/schbul/sbx113. [Epub ahead of print]

Barzilay, R., White, L. K., Calkins, M. E., Moore, T. M., Young, J. F., Wolf, D. H., … Gur, R. E. (2018). Sex-specific association between high traumatic stress exposure and social cognitive functioning in youth. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. In press.

Barzilay, R., Calkins, M. E., Moore, T. M., Wolf, D. H., Satterthwaite, T. D., Cobb Scott, J., … Gur, R. E. (2018). Association between traumatic stress load, psychopathology and cognition in the Philadelphia Neurodevelopmental Cohort. Psychological Medicine. In press.

Wolf, D. H., Satterthwaite, T. D., Calkins, M. E., Ruparel, K., Elliott, M. A., Hopson, R. D., … Gur, R. E. (2015). Functional neuroimaging abnormalities in youth with psychosis spectrum symptoms. JAMA Psychiatry, 72(5), 456–465.

Hestand, M. S., Nowakowska, B. A., Vergaelen, E., Van Houdt, J., Dehaspe, L., Suhl, J. A., … Vermeesch, J. R. (2016).  A catalog of hemizygous variation in 127 22q11 deletion patients. Human Genome Variation, 3, 15065.

Hestand, M. S., Nowakowska, B. A., Vergaelen, E., Van Houdt, J., Dehaspe, L., Suhl, J. A., … Vermeesch, J. R. (2016).  A catalog of hemizygous variation in 127 22q11 deletion patients. Human Genome Variation, 3, 15065.

Satterthwaite, T. D., Connolly, J. J., Ruparel, K., Calkins, M. E., Jackson, C., Elliott, M. A., … Gur, R. E. (2016). The Philadelphia Neurodevelopmental Cohort: A publicly available resource for the study of normal and abnormal brain development in youth. NeuroImage, 124(Part B), 1115–1119.

Satterthwaite, T. D., Wolf, D. H., Calkins, M. E., Vandekar, S. N., Erus, G., Ruparel, K., … Gur, R. E. (2016). Structural Brain Abnormalities in Youth With Psychosis Spectrum Symptoms. JAMA Psychiatry, 73(5), 515–524.

Schmitt, J. E., Yi, J., Calkins, M. E., Ruparel, K., Roalf, D. R., Cassidy, A., … Gur, R. E. (2016). Disrupted anatomic networks in the 22q11.2 deletion syndrome. Neuroimage: Clinical. Neuroimage. Clinical, 12, 420–428.

Shanmugan, S., Wolf, D. H., Calkins, M. E., Moore, T. M., Ruparel, K., Hopson, R. D., … Satterthwaite, T. D. (2016).  Common and Dissociable Mechanisms of Executive System Dysfunction Across Psychiatric Disorders in Youth. The American Journal of Psychiatry, 173(5), 517–526.

Gennatas, E. D., Avants, B. B., Wolf, D. H., Satterthwaite, T. D., Ruparel, K., Ciric, R., … Gur, R. C. (2017). Age-Related Effects and Sex Differences in Gray Matter Density, Volume, Mass, and Cortical Thickness from Childhood to Young Adulthood. The Journal of Neuroscience, 37(20), 5065–5073.

Jones, J. D., Calkins, M. E., Scott, J. C., Bach, E. C., & Gur, Raquel E. (2017). Cannabis use, polysubstance use, and psychosis spectrum symptoms in a community-based sample of US youth. Journal of Adolescent Health, 60(6), 653-659.

Jones, J. D., Scott, J. C., Calkins, M. E., Ruparel, K., Moore, T. M., Gur, R. C., & Gur, R. E. (2016). Correspondence between adolescent and informant reports of substance use: Findings from the Philadelphia Neurodevelopmental Cohort. Addictive Behaviors, 65, 13-18.

Merikangas, A. K., Calkins, M. E., Bilker, W. B., Moore, T. M., Gur, R. C., & Gur, R. E. (2017). Parental Age and Offspring Psychopathology in the Philadelphia Neurodevelopmental Cohort. Journal of the American Academy of Child & Adolescent Psychiatry, 56(5), 391–400.

Weinberger, R., Yi, J., Calkins, M., Guri, Y., McDonald-McGinn, D. M., Emanuel, B. S., … Gothelf, D. (2016). Neurocognitive profile in psychotic versus nonpsychotic individuals with 22q11.2 deletion syndrome. European Neuropsychopharmacology, 26(10), 1610–1618.

Yi, J. J., Weinberger, R., Moore, T. M., Calkins, M. E., Guri, Y., McDonald-McGinn, D. M., … Gur, R. C. (2016). Performance on a computerized neurocognitive battery in 22q11.2 deletion syndrome: A comparison between US and Israeli cohorts. Brain and Cognition, 106, 33–41.

Roalf, D. R., Schmitt, J. E., Vandekar, S. N., Satterthwaite, T. D., Shinohara, R. T., Ruparel, K., … Gur, R. E. (2017). White matter microstructural deficits in 22q11.2 deletion syndrome. Psychiatry Research: Neuroimaging, 268, 35–44.

Tang, S. X., Moore, T. M., Calkins, M. E., Yi, J. J., McDonald-McGinn, D. M., Zackai, E. H., … Gur, R. E. (2017). Emergent, remitted and persistent psychosis-spectrum symptoms in 22q11.2 deletion syndrome. Translational Psychiatry, 7(7), e1180.

Tang, S. X., Moore, T. M., Calkins, M. E., Yi, J. J., Savitt, A., Kohler, C. G., … Gur, R. E. (2017). The psychosis spectrum in 22q11.2 deletion syndrome is comparable to that of nondeleted youths. Biological Psychiatry, 82(1), 17–25.

Xu, Y., Boyd, R., Butler, L., Moore, T., & Benton, T. (2017). Associations of Parent-Adolescent Discrepancies in Family Cohesion and Conflict with Adolescent Impairment. Journal of Child & Family Studies, 26(12), 3360–3369.

White, L. K., Moore, T. M., Calkins, M. E., Wolf, D. H., Satterthwaite, T. D., Leibenluft, E., … Gur, R. E. (2017). An Evaluation of the Specificity of Executive Function Impairment in Developmental Psychopathology. Journal of the American Academy of Child & Adolescent Psychiatry, 56(11), 975–982.